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Institutional Holdings of NEKTAR THERAPEUTICS (NKTR) on 12/31/2011

1. Company Information

Company/StockNEKTAR THERAPEUTICS (stock symbol: NKTR)
Funds Ownership127 out of total 3028 funds (4%) own this stock
Funds own total 108,925,242 shares, 95.49% of all outstanding shares
Funds BOUGHT 6,985,362 more shares (+6.85%) in the quarter ended on 12/31/2011

2. Top 20 Funds Held NKTR in this Quarter (By Shares) Add to Yahoo Finance Message Board

No.FundSharesPut/CallActivity(Shr)% Port.% Out. Shrs
1.)OPPENHEIMER FUNDS INC22,700,000Unchanged0.24%19.90%
2.)HEALTHCOR MANAGEMENT LP10,800,000Added 2.37%2.28%9.47%
3.)PRIMECAP MANAGEMENT CO CA 9,171,956Added 13.55%0.08%8.04%
4.)BVF INC IL7,639,000Added 854.52%14.70%6.70%
5.)VANGUARD GROUP INC5,524,949Added 0.23%0.01%4.84%
6.)ULYS LLC3,975,000Added 44.55%2.35%3.48%
7.)FEDERATED INVESTORS INC PA 3,509,000Cut -11.08%0.10%3.08%
8.)BLACKROCK INSTITUTIONAL TRUST COMPANY NA3,273,124Added 7.34%0.01%2.87%
9.)BLACKROCK FUND ADVISORS3,182,193Added 0.47%0.01%2.79%
10.)STATE STREET CORP3,118,840Cut -3.18%0.00%2.73%
11.)GRANAHAN INVESTMENT MANAGEMENT INC MA2,721,520Cut -1.84%0.58%2.39%
12.)UBS GLOBAL ASSET MANAGEMENT AMERICAS INC2,404,663Added 9.90%0.02%2.11%
13.)FIRST TRUST ADVISORS LP1,938,635Cut -38.72%0.11%1.70%
14.)NEA MANAGEMENT COMPANY LLC1,825,600Unchanged0.35%1.60%
15.)LEGG MASON CAPITAL MANAGEMENT INC1,670,869Cut -1.31%0.13%1.46%
16.)BARCLAYS PLC1,573,000CALLAdded 3,627.49%0.01%1.38%
17.)J P MORGAN CHASE & CO1,517,517Added 27.16%0.00%1.33%
18.)PRICE T ROWE ASSOCIATES INC MD 1,511,500Added 4.14%0.00%1.33%
19.)NORTHERN TRUST CORP1,507,517Cut -0.14%0.00%1.32%
20.)ING INVESTMENT MANAGEMENT CO1,416,605Added 8.68%0.03%1.24%



3. Top 20 Funds Held NKTR in this Quarter (By % of Portfolio) Add to Yahoo Finance Message Board

No.FundSharesPut/CallActivity(Shr)% Port.% Out. Shrs
1.)BVF INC IL7,639,000Added 854.52%14.70%6.70%
2.)ULYS LLC3,975,000Added 44.55%2.35%3.48%
3.)ABINGWORTH LLP663,946Unchanged2.30%0.58%
4.)HEALTHCOR MANAGEMENT LP10,800,000Added 2.37%2.28%9.47%
5.)STRAUS CAPITAL MANAGEMENT LLC 656,722Unchanged1.77%0.58%
6.)HAMBRECHT & QUIST CAPITAL MANAGEMENT LLC1,016,305Added 33.84%1.20%0.89%
7.)ULYS LLC1,200,000CALLAdded 20.00%0.71%1.05%
8.)GRANAHAN INVESTMENT MANAGEMENT INC MA2,721,520Cut -1.84%0.58%2.39%
9.)TIRSCHWELL & LOEWY INC279,150Cut -5.76%0.45%0.24%
10.)CR INTRINSIC INVESTORS LLC1,320,000Added 65.00%0.45%1.16%
11.)FRANKLIN STREET ADVISORS INC NC223,750Cut -9.38%0.42%0.20%
12.)PERIMETER CAPITAL PARTNERS LLC1,025,963Cut -8.49%0.37%0.90%
13.)NEA MANAGEMENT COMPANY LLC1,825,600Unchanged0.35%1.60%
14.)PRINCETON CAPITAL MANAGEMENT INC87,400Added 18.03%0.27%0.08%
15.)OPPENHEIMER FUNDS INC22,700,000Unchanged0.24%19.90%
16.)RED GRANITE ADVISORS LLC79,030Added 104.71%0.19%0.07%
17.)SUFFOLK CAPITAL MANAGEMENT LLC290,100Added 16.04%0.19%0.25%
18.)FIC CAPITAL INC31,900Added 2.24%0.18%0.03%
19.)SPRINGBOK CAPITAL MANAGEMENT LLC67,614Cut -5.23%0.16%0.06%
20.)LEGG MASON CAPITAL MANAGEMENT INC1,670,869Cut -1.31%0.13%1.46%

4. Top 20 Funds BOUGHT NEW NKTR in this Quarter (By Shares) Add to Yahoo Finance Message Board

No.FundSharesPut/Call% Port.% Out. Shrs
1.)INVESCO LTD781,3930.00%0.69%
2.)JEFFERIES GROUP INC DE 601,700CALL0.03%0.53%
3.)MOORE CAPITAL MANAGEMENT LLC550,000CALL0.11%0.48%
4.)CR INTRINSIC INVESTORS LLC250,000CALL0.09%0.22%
5.)JACOBS LEVY EQUITY MANAGEMENT INC190,6000.02%0.17%
6.)WEISS GEORGE A155,7160.03%0.14%
7.)CAXTON ASSOCIATES LLC56,0710.01%0.05%
8.)ZURCHER KANTONALBANK (ZURICH CANTONALBANK)55,0000.01%0.05%
9.)TWO SIGMA INVESTMENTS LLC17,9450.00%0.02%
10.)GENESEE VALLEY TRUST CO16,2500.08%0.01%
11.)GUGGENHEIM CAPITAL LLC13,0910.00%0.01%
12.)TWO SIGMA ADVISERS LLC11,6350.00%0.01%
13.)BNP PARIBAS ARBITRAGE SNC11,1570.00%0.01%
14.)BNP PARIBAS ARBITRAGE SA11,1570.00%0.01%
15.)SAC CAPITAL ADVISORS LP9,2480.00%0.01%
16.)JEFFERIES GROUP INC DE 6,4280.00%0.01%
17.)QUANTBOT TECHNOLOGIES LLC4,8000.04%0.00%
18.)SPOT TRADING LLC2,2000.00%0.00%
19.)LADENBURG THALMANN FINANCIAL SERVICES INC8000.00%0.00%
20.)GLOBAL X MANAGEMENT CO LLC4840.00%0.00%

5. Top 20 Funds SOLD OUT NKTR in this Quarter (By Shares) Add to Yahoo Finance Message Board

No.FundSharesPut/Call% Port.% Out. Shrs
1.)COLUMBUS CIRCLE INVESTORS470,9970.02%0.41%
2.)MOORE CAPITAL MANAGEMENT LLC300,0000.05%0.26%
3.)CALIFORNIA PUBLIC EMPLOYEES RETIREMENT SYSTEM129,1040.00%0.11%
4.)ARNHOLD & S BLEICHROEDER ADVISERS LLC125,0000.00%0.11%
5.)PARAMETRICA MANAGEMENT LTD46,5620.17%0.04%
6.)AXA FINANCIAL INC44,7850.00%0.04%
7.)SHAPIRO ROBERT N28,9520.05%0.03%
8.)PRINCIPAL FINANCIAL GROUP INC20,5850.00%0.02%
9.)KNIGHT CAPITAL GROUP INC20,1980.00%0.02%
10.)PEAK6 INVESTMENTS LP16,5060.00%0.01%
11.)RCM CAPITAL MANAGEMENT LLC12,7400.00%0.01%
12.)RODNEY SQUARE MANAGEMENT CORP12,5220.01%0.01%
13.)APERIO GROUP LLC10,5800.00%0.01%
14.)CREDIT AGRICOLE S A4,5000.00%0.00%
15.)LOS ANGELES CAPITAL MANAGEMENT & EQUITY RESEARCH INC9500.00%0.00%