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Institutional Holdings of LIGAND PHARMACEUTICALS INCORPORATED (LGND) on 12/31/2011

1. Company Information

Company/StockLIGAND PHARMACEUTICALS INCORPORATED (stock symbol: LGND)
Funds Ownership67 out of total 3028 funds (2%) own this stock
Funds own total 10,919,137 shares, 55.60% of all outstanding shares
Funds SOLD -1,889,532 shares (-14.75%) in the quarter ended on 12/31/2011

2. Top 20 Funds Held LGND in this Quarter (By Shares) Add to Yahoo Finance Message Board

No.FundSharesPut/CallActivity(Shr)% Port.% Out. Shrs
1.)BVF INC IL3,476,044Added 23.97%14.19%17.70%
2.)WELLINGTON MANAGEMENT CO LLP1,221,353Cut -24.96%0.01%6.22%
3.)VANGUARD GROUP INC975,048Cut -18.59%0.00%4.96%
4.)FMR LLC597,700Added 138.32%0.00%3.04%
5.)DEUTSCHE BANK AG 596,673Added 11.24%0.01%3.04%
6.)BLACKROCK INSTITUTIONAL TRUST COMPANY NA566,768Added 7.87%0.00%2.89%
7.)BLACKROCK FUND ADVISORS553,815Cut -0.51%0.00%2.82%
8.)STATE STREET CORP415,309Cut -3.45%0.00%2.11%
9.)ASHFORD CAPITAL MANAGEMENT INC415,100New0.84%2.11%
10.)NORTHERN TRUST CORP262,268Cut -1.12%0.00%1.34%
11.)PARK WEST ASSET MANAGEMENT LLC224,632New0.55%1.14%
12.)STATE OF WISCONSIN INVESTMENT BOARD115,000New0.01%0.59%
13.)DIMENSIONAL FUND ADVISORS INC106,275New0.00%0.54%
14.)TIAA CREF INVESTMENT MANAGEMENT LLC95,982Cut -4.28%0.00%0.49%
15.)ALLIANZ GLOBAL INVESTORS OF AMERICA L P92,300Added 21.93%0.00%0.47%
16.)BANK OF NEW YORK MELLON CORP92,181Added 14.46%0.00%0.47%
17.)D E SHAW & CO INC84,444Added 2.12%0.00%0.43%
18.)BAKER BROS ADVISORS LLC73,401New0.03%0.37%
19.)JACOBS LEVY EQUITY MANAGEMENT INC69,220New0.01%0.35%
20.)TECHNICAL FINANCIAL SERVICES LLC58,431Cut -64.25%0.04%0.30%



3. Top 20 Funds Held LGND in this Quarter (By % of Portfolio) Add to Yahoo Finance Message Board

No.FundSharesPut/CallActivity(Shr)% Port.% Out. Shrs
1.)BVF INC IL3,476,044Added 23.97%14.19%17.70%
2.)ASHFORD CAPITAL MANAGEMENT INC415,100New0.84%2.11%
3.)PARK WEST ASSET MANAGEMENT LLC224,632New0.55%1.14%
4.)COVALENT PARTNERS LLC36,500New0.17%0.19%
5.)SCM ADVISORS LLC11,580New0.15%0.06%
6.)PETERSEN FLYNN & DINSMORE INC15,625Added 5.97%0.08%0.08%
7.)TECHNICAL FINANCIAL SERVICES LLC58,431Cut -64.25%0.04%0.30%
8.)BRIDGEWAY CAPITAL MANAGEMENT INC57,333Added 0.35%0.04%0.29%
9.)SMITH ASSET MANAGEMENT GROUP LP55,030Cut -7.08%0.03%0.28%
10.)BAKER BROS ADVISORS LLC73,401New0.03%0.37%
11.)NJ STATE EMPLOYEES DEFERRED COMPENSATION PLAN6,666Unchanged0.02%0.03%
12.)JACOBS LEVY EQUITY MANAGEMENT INC69,220New0.01%0.35%
13.)PAX WORLD MANAGEMENT CORP14,000Unchanged0.01%0.07%
14.)OXFORD ASSET MANAGEMENT27,177Cut -26.78%0.01%0.14%
15.)DEUTSCHE BANK AG 596,673Added 11.24%0.01%3.04%
16.)STATE OF WISCONSIN INVESTMENT BOARD115,000New0.01%0.59%
17.)WELLINGTON MANAGEMENT CO LLP1,221,353Cut -24.96%0.01%6.22%
18.)DEKABANK DEUTSCHE GIROZENTRALE15,000Unchanged0.00%0.08%
19.)BLACKROCK FUND ADVISORS553,815Cut -0.51%0.00%2.82%
20.)ALLIANZ GLOBAL INVESTORS OF AMERICA L P92,300Added 21.93%0.00%0.47%

4. Top 20 Funds BOUGHT NEW LGND in this Quarter (By Shares) Add to Yahoo Finance Message Board

No.FundSharesPut/Call% Port.% Out. Shrs
1.)ASHFORD CAPITAL MANAGEMENT INC415,1000.84%2.11%
2.)PARK WEST ASSET MANAGEMENT LLC224,6320.55%1.14%
3.)STATE OF WISCONSIN INVESTMENT BOARD115,0000.01%0.59%
4.)DIMENSIONAL FUND ADVISORS INC106,2750.00%0.54%
5.)BAKER BROS ADVISORS LLC73,4010.03%0.37%
6.)JACOBS LEVY EQUITY MANAGEMENT INC69,2200.01%0.35%
7.)COVALENT PARTNERS LLC36,5000.17%0.19%
8.)SCHWAB CHARLES INVESTMENT MANAGEMENT INC26,7480.00%0.14%
9.)SUSQUEHANNA INTERNATIONAL GROUP LLP21,9130.00%0.11%
10.)JEFFERIES GROUP INC DE 17,0720.00%0.09%
11.)HIGHBRIDGE CAPITAL MANAGEMENT LLC14,4540.00%0.07%
12.)SUSQUEHANNA INTERNATIONAL GROUP LLP13,200PUT0.00%0.07%
13.)AQR CAPITAL MANAGEMENT LLC12,8000.00%0.07%
14.)SCM ADVISORS LLC11,5800.15%0.06%
15.)MILLENNIUM MANAGEMENT LLC11,0070.00%0.06%
16.)PANAGORA ASSET MANAGEMENT INC8,1670.00%0.04%
17.)RUSSELL FRANK CO 4,9960.00%0.03%
18.)CREATIVE PLANNING1000.00%0.00%

5. Top 20 Funds SOLD OUT LGND in this Quarter (By Shares) Add to Yahoo Finance Message Board

No.FundSharesPut/Call% Port.% Out. Shrs
1.)KNOTT DAVID M1,639,7062.79%8.35%
2.)THIRD POINT LLC705,0160.46%3.59%
3.)EUDAIMONIA ASSET MANAGEMENT LLC129,5360.97%0.66%
4.)DRIEHAUS CAPITAL MANAGEMENT LLC104,3100.08%0.53%
5.)RENAISSANCE TECHNOLOGIES LLC50,1050.00%0.26%
6.)GRT CAPITAL PARTNERS LLC24,9180.13%0.13%
7.)COWEN GROUP INC20,000PUT0.04%0.10%
8.)ROCKEFELLER FINANCIAL SERVICES INC12,2700.01%0.06%
9.)HATTERAS ALTERNATIVE MUTUAL FUNDS LLC12,1000.17%0.06%
10.)UNIONBANCAL CORP7,5000.00%0.04%
11.)AXA FINANCIAL INC6,1290.00%0.03%
12.)ROYAL BANK OF CANADA 1,5730.00%0.01%
13.)US BANCORP DE 320.00%0.00%
14.)LOS ANGELES CAPITAL MANAGEMENT & EQUITY RESEARCH INC160.00%0.00%