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Institutional Holdings of ALEXION PHARMACEUTICALS, INC. (ALXN) on 12/31/2011

1. Company Information

Company/StockALEXION PHARMACEUTICALS, INC. (stock symbol: ALXN)
Funds Ownership353 out of total 3028 funds (12%) own this stock
Funds own total 165,856,482 shares, 89.17% of all outstanding shares
Funds SOLD -2,662,323 shares (-1.58%) in the quarter ended on 12/31/2011

2. Top 20 Funds Held ALXN in this Quarter (By Shares) Add to Yahoo Finance Message Board

No.FundSharesPut/CallActivity(Shr)% Port.% Out. Shrs
1.)FMR LLC21,273,525Cut -8.41%0.31%11.44%
2.)PRICE T ROWE ASSOCIATES INC MD 14,488,395Added 0.37%0.36%7.79%
3.)CAPITAL RESEARCH GLOBAL INVESTORS13,328,122Added 7.01%0.43%7.17%
4.)SANDS CAPITAL MANAGEMENT LLC8,789,249Added 0.20%3.62%4.73%
5.)WELLS FARGO & CO MN8,055,958Added 16.26%0.42%4.33%
6.)VANGUARD GROUP INC7,628,402Added 3.17%0.09%4.10%
7.)JENNISON ASSOCIATES LLC6,549,698Cut -99.39%0.66%3.52%
8.)COLUMBIA WANGER ASSET MANAGEMENT LP4,728,340Cut -24.76%1.65%2.54%
9.)BLACKROCK INSTITUTIONAL TRUST COMPANY NA4,516,583Added 11.70%0.08%2.43%
10.)AMERICAN CENTURY COMPANIES INC3,670,769Added 7.53%0.43%1.97%
11.)AMERIPRISE FINANCIAL INC3,636,031Cut -26.62%0.20%1.95%
12.)VIKING GLOBAL INVESTORS LP3,343,896Added 369.78%2.49%1.80%
13.)STATE STREET CORP3,206,833Cut -1.46%0.04%1.72%
14.)J P MORGAN CHASE & CO3,156,102Added 8.57%0.10%1.70%
15.)UBS GLOBAL ASSET MANAGEMENT AMERICAS INC3,087,263Cut -13.37%0.35%1.66%
16.)BLACKROCK FUND ADVISORS2,446,581Cut -1.44%0.09%1.32%
17.)INVESCO LTD2,347,651Added 11.93%0.10%1.26%
18.)JANUS CAPITAL MANAGEMENT LLC1,841,471New0.15%0.99%
19.)TURNER INVESTMENT PARTNERS INC1,806,581Cut -3.44%1.17%0.97%
20.)BANK OF NEW YORK MELLON CORP1,790,312Cut -5.99%0.05%0.96%



3. Top 20 Funds Held ALXN in this Quarter (By % of Portfolio) Add to Yahoo Finance Message Board

No.FundSharesPut/CallActivity(Shr)% Port.% Out. Shrs
1.)MARCUARD FAMILY OFFICE LTD186,666New14.18%0.10%
2.)FITZGERALD THOMAS H JR CT 75,300New6.45%0.04%
3.)DE BURLO GROUP INC211,600Added 0.05%5.91%0.11%
4.)ORACLE INVESTMENT MANAGEMENT INC395,932Unchanged4.42%0.21%
5.)HAMBRECHT & QUIST CAPITAL MANAGEMENT LLC293,329Added 39.13%4.41%0.16%
6.)PREMIER ASSET MANAGMENT LLC94,100Cut -19.14%4.34%0.05%
7.)MAGEE THOMSON INVESTMENT PARTNERS LLC273,817Cut -3.18%4.07%0.15%
8.)NORTHCOAST ASSET MANAGEMENT LLC363,156Cut -31.71%3.65%0.20%
9.)BB BIOTECH AG450,000Unchanged3.62%0.24%
10.)SANDS CAPITAL MANAGEMENT LLC8,789,249Added 0.20%3.62%4.73%
11.)ANTIPODEAN ADVISORS LLC191,000New3.21%0.10%
12.)CNH PARTNERS LLC374,970Unchanged3.15%0.20%
13.)BENNETT LAWRENCE MANAGEMENT L L C NY191,255Cut -26.06%2.83%0.10%
14.)BENDER ROBERT & ASSOCIATES40,223Cut -0.22%2.77%0.02%
15.)VIKING GLOBAL INVESTORS LP3,343,896Added 369.78%2.49%1.80%
16.)REDWOOD INVESTMENTS LLC164,674Cut -14.43%1.98%0.09%
17.)SCM ADVISORS LLC23,972Cut -12.39%1.85%0.01%
18.)MARVIN & PALMER ASSOCIATES INC174,300Cut -52.02%1.84%0.09%
19.)COLUMBIA WANGER ASSET MANAGEMENT LP4,728,340Cut -24.76%1.65%2.54%
20.)CENTURY CAPITAL MANAGEMENT LLC531,550Cut -34.29%1.58%0.29%

4. Top 20 Funds BOUGHT NEW ALXN in this Quarter (By Shares) Add to Yahoo Finance Message Board

No.FundSharesPut/Call% Port.% Out. Shrs
1.)JANUS CAPITAL MANAGEMENT LLC1,841,4710.15%0.99%
2.)EULAV ASSET MANAGEMENT257,6001.22%0.14%
3.)GENEVA INVESTMENT MANAGEMENT OF CHICAGO LLC232,4990.51%0.13%
4.)ANTIPODEAN ADVISORS LLC191,0003.21%0.10%
5.)MARCUARD FAMILY OFFICE LTD186,66614.18%0.10%
6.)MADISON SQUARE INVESTORS LLC164,0520.13%0.09%
7.)ARROWSTREET CAPITAL LIMITED PARTNERSHIP159,4160.10%0.09%
8.)ZURCHER KANTONALBANK (ZURICH CANTONALBANK)80,8540.27%0.04%
9.)JACOBS LEVY EQUITY MANAGEMENT INC78,7200.09%0.04%
10.)FITZGERALD THOMAS H JR CT 75,3006.45%0.04%
11.)FJARDE AP FONDEN (THE FOURTH SWEDISH NATIONAL PENSIONFUND)69,5020.12%0.04%
12.)ANDRA AP FONDEN66,5000.16%0.04%
13.)1798 GLOBAL PARTNERS (CAYMAN ISLANDS) LTD64,6150.44%0.03%
14.)QUANTITATIVE INVESTMENT MANAGEMENT LLC52,9000.32%0.03%
15.)TOBAM45,3000.56%0.02%
16.)ROBECO INSTITUTIONAL ASSET MANAGEMENT BV41,7050.04%0.02%
17.)VAN ECK ASSOCIATES CORP41,4540.01%0.02%
18.)MOODY LYNN & CO 39,5900.55%0.02%
19.)BATTERYMARCH FINANCIAL MANAGEMENT INC39,4900.04%0.02%
20.)PEAK6 INVESTMENTS LP35,100CALL0.01%0.02%

5. Top 20 Funds SOLD OUT ALXN in this Quarter (By Shares) Add to Yahoo Finance Message Board

No.FundSharesPut/Call% Port.% Out. Shrs
1.)JANUS CAPITAL MANAGEMENT LLC2,266,8740.18%1.22%
2.)TIAA CREF INVESTMENT MANAGEMENT LLC2,179,8930.15%1.17%
3.)AXA FINANCIAL INC575,0900.24%0.31%
4.)TEACHERS ADVISORS INC558,8280.18%0.30%
5.)FIRST TRUST ADVISORS LP521,7700.38%0.28%
6.)TWO SIGMA INVESTMENTS LLC379,3140.36%0.20%
7.)ALYESKA INVESTMENT GROUP LP308,7410.54%0.17%
8.)EULAV ASSET MANAGEMENT LLC293,6001.32%0.16%
9.)PUTNAM INVESTMENT MANAGEMENT LLC242,1060.06%0.13%
10.)MADISON SQUARE INVESTORS LLC184,2610.13%0.10%
11.)KAYNE ANDERSON RUDNICK INVESTMENT MANAGEMENT LLC144,6860.27%0.08%
12.)OXFORD ASSET MANAGEMENT84,9650.16%0.05%
13.)GW CAPITAL MANAGEMENT LLC70,0000.15%0.04%
14.)ING INVESTMENT MANAGEMENT (EUROPE) BV57,1280.04%0.03%
15.)SANTA FE PARTNERS LLC45,7650.48%0.02%
16.)ROYAL LONDON ASSET MANAGEMENT LTD33,4730.11%0.02%
17.)CAPITAL MANAGEMENT ASSOCIATES INC31,1353.70%0.02%
18.)DNB NOR ASSET MANAGEMENT AS20,7080.03%0.01%
19.)REINHART MAHONEY CAPITAL MANAGEMENT INC19,1100.16%0.01%
20.)KNIGHT CAPITAL GROUP INC18,2820.02%0.01%