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Fund Holdings of ORBIMED ADVISORS LLC Filed on 2012-02-14

Link to Original SEC 13F filings sorted on filing date: 2012-02-14 | 2011-11-14 | 2011-08-15 | 2011-05-16 | 2011-02-14 | 2010-11-15 | 2010-08-16 | 2010-05-17 | 2010-02-16 | 2009-11-16 | 2009-08-14 | 2009-05-15 | 2009-02-17 | 2008-11-14 | 2008-08-14 | 2008-05-15 |

1. Fund Information

Fund NameORBIMED ADVISORS LLC
Fund Manager
Address601 LEXINGTON AVENUE, 54TH FLOOR
NEW YORK, NY, 10022
::Google Map
Phone(212) 739-6400
13F Asset Last Qtr$2,693,953,000
13F Asset This Qtr$3,049,023,000
Asset Change13.18%

2. Comparison of Holdings by Sectors with Last Quarter

3. Top 20 Holdings (Value) of This Quarter

No.SecurityPut/CallStockSharesValue(x$1000)Activity(Shr)% Port.
1.)PFIZER INCPFE8,055,600$174,323Added 3.87%5.72%
2.)BRISTOL-MYERS SQUIBB CO.BMY3,880,400$136,745Added 15.32%4.48%
3.)WELLPOINT INCWLP1,686,900$111,757Cut -8.23%3.67%
4.)ALLERGAN, INCAGN1,254,200$110,044Cut -10.43%3.61%
5.)PHARMASSET, INC.VRUS849,700$108,932Added 8.69%3.57%
6.)MERCK & CO., INCMRK2,385,500$89,933Cut -13.22%2.95%
7.)GILEAD SCIENCES, INC.GILD2,180,700$89,256Cut -9.59%2.93%
8.)UNITEDHEALTH GROUP INCUNH1,758,900$89,141Cut -3.64%2.92%
9.)AETNA INC.AET2,036,000$85,899Added 9.82%2.82%
10.)PHARMASSET, INC.CALLVRUS650,000$83,330Added 550.00%2.73%
11.)INCYTE CORPORATIONINCY5,273,100$79,149Added 19.79%2.60%
12.)HUMANA INC.HUM858,100$75,178Cut -3.04%2.47%
13.)WATSON PHARMACEUTICALS, INC.WPI1,160,300$70,013Added 0.71%2.30%
14.)WARNER CHILCOTT PLCWCRX4,246,100$64,243Added 1.06%2.11%
15.)THERMO FISHER SCIENTIFIC INCTMO1,370,100$61,613Added 5.00%2.02%
16.)MEDCO HEALTH SOLUTIONS, INC.MHS1,087,400$60,786Added 532.21%1.99%
17.)VIVUS, INC.VVUS6,164,000$60,099Added 13.68%1.97%
18.)LIFE TECHNOLOGIES CORPORATIONLIFE1,536,800$59,797Added 6.49%1.96%
19.)CELGENE CORPORATIONCELG834,000$56,378Added 222.01%1.85%
20.)BIOMARIN PHARMACEUTICAL INC.BMRN1,639,200$56,356Cut -0.77%1.85%

4. Top 20 (Value) Holdings BOUGHT NEW in This Quarter

No.SecurityPut/CallStockShares NEWValue(x$1000)% Port.
1.)ABBOTT LABORATORIESABT612,000$34,4131.13%
2.)BRISTOL-MYERS SQUIBB CO.CALLBMY500,000$17,6200.58%
3.)QUESTCOR PHARMACEUTICALS, INC.QCOR345,200$14,3530.47%
4.)AMGEN INC.PUTAMGN200,000$12,8420.42%
5.)LILLY (ELI) & CO.CALLLLY275,000$11,4290.37%
6.)INTERMUNE, INC.ITMN493,400$6,2170.20%
7.)UNITED THERAPEUTICS CORPORATIONCALLUTHR100,000$4,7250.15%
8.)UNITED THERAPEUTICS CORPORATIONUTHR97,500$4,6070.15%
9.)SALIX PHARMACEUTICALS, LTD.SLXP64,700$3,0960.10%
10.)INCYTE CORPORATIONCALLINCY200,000$3,0020.10%
11.)CELSION CORPORATIONCLSN1,513,514$2,5730.08%
12.)AFFYMAX, INC.CALLAFFY200,000$1,3220.04%
13.)SINOVAC BIOTECH LTDSVA249,000$5480.02%
14.)TARGACEPT, INC.TRGT31,100$1730.01%
15.)XENOPORT, INC.PUTXNPT25,000$950.00%

5. Top 20 (Value) Holdings Totally SOLD OUT in This Quarter

No.SecurityPut/CallStockShares SOLDValue(x$1000)% Port. Last Qtr
1.)ILLUMINA, INC.ILMN821,900$33,6321.25%
2.)ISHARES TRUST - NASDAQ BIOTECHNOLOGY INDEXPUTIBB350,000$32,6731.21%
3.)TEVA PHARMACEUTICAL INDUSTRIES LIMITED - AMERICAN DEPOSITARY SHARES, EACH REPRESENTING ONETEVA536,900$19,9830.74%
4.)HOSPIRA INCHSP510,000$18,8700.70%
5.)VERTEX PHARMACEUTICALS INCORPORATEDPUTVRTX230,000$10,2260.38%
6.)PHARMASSET, INC.PUTVRUS100,000$8,2370.31%
7.)ONYX PHARMACEUTICALS, INC.CALLONXX250,000$7,5030.28%
8.)ARQULE, INC.ARQL1,240,900$6,2670.23%
9.)VALEANT PHARMACEUTICALS INTERNATIONAL INCCALLVRX150,000$5,5680.21%
10.)ONCOTHYREON INC . - COMMON SHARESONTY700,000$4,1860.16%
11.)ANADYS PHARMACEUTICALS, INC.ANDS4,140,800$3,7680.14%
12.)ONYX PHARMACEUTICALS, INC.ONXX80,200$2,4070.09%
13.)MEDIVATION, INC.CALLMDVN75,000$1,2740.05%
14.)SAVIENT PHARMACEUTICALS INCPUTSVNT250,000$1,0250.04%
15.)ALNYLAM PHARMACEUTICALS, INC.ALNY44,700$2940.01%